This Article  • References  • Full text PDF  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Contact me when this article is cited  Related Content  • Similar articles in JAMA  Social Bookmarking   What's this?

Giovanni Rezza; Francesca Menniti-Ippolito; Adriano Lazzarin; Gioacchino Angarano; Alessandro Sinicco; Roberto Zerboni; Umberto Tirelli
Italian Multiple Cohort Study on AIDS National Institute of Health Rome, Italy

JAMA. 1990;263(3):372-373.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

To the Editor.—

Kaslow et al¹ found that psychoactive substance use did not accelerate the progression toward acquired immunodeficiency syndrome (AIDS) in a large cohort of homosexual men. However, as reported by the authors, the numbers of intravenous drug and opiate users were small.

In previous studies, frequent drug injection was found to be associated with T4-cell loss.² However, the relationship between continued drug injection and incidence of AIDS in infected subjects remains unclear. We are conducting a cohort study to estimate the risk of developing AIDS in human immunodeficiency virus seroconverters who are intravenous drug users (IVDUs).³ Most of them admitted to continued drug injection, mainly heroin injection, after human immunodeficiency virus seroconversion. To study the role played by drug injection in the progression of human immunodeficiency virus infection, we compared the incidence of AIDS in 261 seropositive IVDUs to that in 89 non—drug-injecting homosexual men. . . . [Full Text PDF of this Article]

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?