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Jolanta Gromadziska, PhD; Maria Skodowska, PhD
Lodz, Poland

JAMA. 1990;263(7):949-950.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

To the Editor.—

I read with interest the article by Kok et al.¹ The authors state that data on erythrocyte (red blood cell) glutathione peroxidase (GSH-Px) (EC 1.11.1.9) activity in patients who have had a myocardial infarction have not been published.

We are working on this problem. It is known that GSH-Px is one of the major enzymes involved in the protection of the cell against antiperoxidation, particularly the cells of heart muscle. Selenium-containing GSH-Px acts on hydrogen peroxide and lipids or other organic hydroperoxides.² Doroshow et al³ found that in heart tissue catalase was almost absent and superoxide dismutase had only 27% of the activity found in liver. Only GSH-Px activity is high both in liver and in heart tissues. Batist et al⁴ demonstrated that changes in this enzyme in heart cells and in erythrocytes are well correlated.

Study.—

We determined red blood cell GSH-Px . . . [Full Text PDF of this Article]

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