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James D. Watson, PhD
National Center for Human Genome Research National Institutes of Health Bethesda, Md

JAMA. 1990;264(22):2867.

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In Reply.—

Dr Yaes questions the value of the Human Genome Project because he believes the money would be better spent on other research. In response, I want to make several points.

The projected funding rate at the National Institutes of Health (NIH) is 25% of approved grants, not 15% or 20% as he suggests. While it is regrettable that more grants cannot be funded, the genome project does fund many investigators who otherwise would be competing for funding from other NIH programs. I believe that the genome project will attract many young investigators to biomedical science rather than discourage them. In fiscal year 1989, twenty-eight percent of genome grants went to young investigators. They recognize that the program will provide them with improved tools for studying genes and their function.

The availability of a genetic test for a specific disease can lead to improved and earlier diagnosis as well . . . [Full Text PDF of this Article]

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