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Frederick Van Lente, PhD; William Cornell, MD
Cleveland (Ohio) Clinic Foundation

JAMA. 1990;264(23):2991-2992.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

To the Editor.—

In their report of "Myopathy and Rhabdomyolysis Associated With Lovastatin-Gemfibrozil Combination Therapy," Pierce et al¹ present a case in which they describe parenthetically the presence of 44% creatine kinase—MB (CK-MB) in the serum of a patient without clear evidence of cardiac injury. Unfortunately, they did not offer further explanation for this finding.

It has become increasingly clear that the process of recovery from severe skeletal muscle injury leads to an obvious change in the expression of creatine kinase isoenzymes.² However, the extent of this change has not been fully explored, and confusion remains regarding the significance of changes in the percentage of CK-MB percentage in serum. We wish to report a case that demonstrates how significantly the CK-MB percentage can increase after severe rhabdomyolysis.

Report of a Case.—

An 18-year-old woman underwent an unremarkable cesarean section delivery of a healthy, full-term infant following prolonged rupture . . . [Full Text PDF of this Article]

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