To the Editor. —
The improved outcomes for low—birth-weight infants born in the 1970s might account for a portion of the increase in asthma morbidity and mortality in the United States for the period 1980 through 1987 as documented by Weiss and Wagener.1
With the evolution of perinatal medicine and the widespread development of neonatal intensive care units, the neonatal death rate for very low—birth-weight infants plummeted (Table).
However, many of these survivors of neonatal intensive care units were plagued with long-term disabilities, such as bronchopulmonary dysplasia, that would put them at risk for chronic respiratory diseases such as asthma.2
It is possible that, as this cohort of high-risk survivors, which was disproportionately poor, nonwhite, and urban (the location of the neonatal intensive care units), became young children in the 1980s, those who developed asthma experienced an increased morbidity and mortality because of decreased primary care access secondary
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