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  Vol. 266 No. 19, November 20, 1991 TABLE OF CONTENTS
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Subcutaneous Sumatriptan in Acute Migraine-Reply

Roger K. Cady, MD
The Shealy Institute Springfield, Mo

JAMA. 1991;266(19):2703-2704.

Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

In Reply.

—Dr Korenfeld raises the question of whether visual disturbances associated with subcutaneous sumatriptan could have resulted from relative ischemia secondary to posterior ciliary artery or central renal artery vasoconstriction.

When we reviewed the patients who were experiencing visual difficulties, we noted that seven of the 734 sumatriptan-treated patients had true visual disturbances. These complaints generally began minutes after the subcutaneous injection of sumatriptan and resolved within several minutes to 1 hour. In only a single patient who received a second dose of sumatriptan was the visual disturbance duplicated by the second injection. No long-term visual complaints were noted except in a single patient who had blurred vision in one eye, which began several hours after the sumatriptan injection, and a subsequent ophthalmologic evaluation concluded that this problem was secondary to her severe myopia and not to sumatriptan.

Whether the posterior ciliary artery or the central retinal artery has . . . [Full Text PDF of this Article]



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