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Zidovudine Does It Work for Everyone?
Mark D. Smith, MD, MBA
JAMA. 1991;266(19):2750-2751.
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| Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings. |
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Over 85 000 (45%) of reported acquired immunodeficiency syndrome (AIDS) cases in the United States have occurred among racial and ethnic minorities including blacks, Hispanics, Asian-Pacific islanders, and native American or Alaskan native people.1 This number, of course, represents only those reported with the later stages of the human immunodeficiency virus (HIV) infection; studies in a variety of populations have also demonstrated rates of asymptomatic HIV infection substantially higher in people of color than in whites. Women also represent a growing number of those with AIDS—9% of adult and adolescent cases diagnosed before August 1990 and 12% in the last year. But the representation of minorities and women among AIDS cases stands in stark contrast to their underrepresentation in the clinical trials of drugs directed against HIV. Most clinical trials have been overwhelmingly composed of gay white men; minorities, women, and injecting drug
. . . [Full Text PDF of this Article]
Author Affiliations
From the Henry J. Kaiser Family Foundation, Menlo Park, Calif.
Footnotes
Reprint requests to the Henry J. Kaiser Family Foundation, 2400 Sand Hill Rd, Menlo Park, CA 94025 (Dr Smith).
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