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Chlamydial Pneumonia and Asthma: A Potentially Important Relationship
Roger C. Bone, MD
JAMA. 1991;266(2):265.
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| Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings. |
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In this issue of JAMA, Hahn et al1 document an interesting relationship between chlamydial pneumonia and asthma in adults using a matched comparison method. These investigators found that patients with serologically confirmed Chlamydia pneumoniae infection (antibody titers greater than 1:64) were much more likely to develop bronchial asthma subsequent to their chlamydial infection than were seronegative patients (antibody titers less than 1:16). Nearly 30% of the Chlamydia-exposed (seropositive) patients were later diagnosed as having asthmatic bronchitis, whereas only 7% of unexposed (seronegative) patients received the same diagnosis in the 6-month period after their respiratory illness.
The context for this finding is a trend toward increasing incidence, morbidity, and mortality attributable to asthma— despite advances in diagnosis and treatment. During the 1980s, statistics relating to asthma showed distinct increases in mortality in the United States and in most industrialized countries.2,3 Furthermore, a recent article demonstrated
. . . [Full Text PDF of this Article]
Author Affiliations
From the Section of Pulmonary Medicine, Rush-Presbyterian-St Luke's Medical Center, Chicago, Ill.
Footnotes
Reprint requests to Section of Pulmonary Medicine, Rush-Presbyterian-St Luke's Medical Center and Rush Medical College of Rush University, 1653 W Congress Pkwy, Chicago, IL 60612 (Dr Bone).
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