This Article  • References  • Full text PDF  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citation map  • Citing articles on HighWire  • Citing articles on Web of Science (10)  • Contact me when this article is cited  Related Content  • Similar articles in JAMA  Social Bookmarking   What's this?

Edward Connor, MD

JAMA. 1991;266(24):3474-3475.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

Early intervention using antiretroviral therapy and prophylaxis for infections has become the standard of care for adults and children infected with human immunodeficiency virus (HIV). Advances in the field of HIV treatment have resulted in improvement in quality and/or duration of life for patients of all ages. Zidovudine therapy is now approved and routinely indicated for treatment of symptomatic HIV-infected children and for those with evidence of immunodeficiency.¹ Prophylaxis for Pneumocystis carinii pneumonia is routinely recommended for children with significant CD4 lymphocyte depletion, and intravenous -globulin has been shown to reduce the rate of serious bacterial infections in some HIV-infected chiidren.^2,3 However, for therapeutic interventions to be applied optimally, it is essential for the diagnosis of HIV infection to be made as early in the course as possible, before immunodeficiency and symptomatic illness are manifest. For children with perinatally acquired HIV infection, this is particularly problematic.^4,5 . . . [Full Text PDF of this Article]

Author Affiliations
From the Department of Pediatrics, Division of Allergy, Immunology, and Infectious Disease, UMD—New Jersey Medical School, and Children's Hospital of New Jersey, Newark.

Footnotes
Reprint requests to Department of Pediatrics, Division of Allergy, Immunology, and Infectious Disease, UMD—New Jersey Medical School, 185 S Orange Ave, University Heights, Newark, NJ 07103-2714 (Dr Connor).

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?