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Drummond Rennie, MD; Annette Flanagin, RN, MA
American Medical Association Chicago, Ill

JAMA. 1992;267(21):2892.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

In Reply.

—We agree with Liberati to the extent that the registration of trials will be of use first to meta-analysts. But we predict that in the future all medical practitioners will come to base their practices on the results of such formal critical reviews. The fact that at this time many physicians are unskilled in the critical appraisal of the research literature does not mean that all are. Nor does it mean that we should abandon trying to improve such appraisal or stop publishing the research on which these reviews are based.

Liberati's suggestion of a two-stage editorial review process, as he says, is not new. In fact, the first stage of this . . . [Full Text PDF of this Article]

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