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Coffee and Plasma Lipid Levels-Reply
Roy E. Fried, MD, MHS
Kaiser Permanente Washington, DC
Peter O. Kwiterovich, MD;
Lora B. Wilder, ScD, RD;
Taryn F. Moy, MS, RD
The Johns Hopkins Medical Institutions Baltimore, Md
Thomas A. Pearson, MD, PhD
Mary Imogene Bassett Research Institute Cooperstown, NY
JAMA. 1992;268(14):1858-1859.
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In Reply.
—We thank Dr Kokjohn for her interest in our study and offer these answers to her questions.
The 90th percentile of plasma total cholesterol levels for age was determined by the Lipid Research Clinics Prevalence Study.1 Morbid obesity was defined as a body weight equal to or greater than 200% of ideal body weight for height, defined as the midpoint of the weight range for mediumframed men at given heights from Metropolitan Life Insurance Company tables of 1959.2
All subjects assigned to drink coffee were asked to prepare their coffee using the same recipe, so that the treatment would remain consistent throughout the study for all subjects, and still permit enough additional coffee to be prepared for a spouse or other family member without the inconvenience of brewing two separate carafes of coffee. Data on compliance indicate that this did not lead to protocol violations.
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