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Charles H. Kirkpatrick, MD; David T. Rowlands, Jr, MD

JAMA. 1992;268(20):2952-2958.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

FROM THE uncertain and often unsuccessful attempts in the 1950s and early 1960s, organ and tissue transplantations have become major forms of definitive treatment for many kinds of organ failure. Corneal transplantation has restored sight to thousands of persons, and skin grafts are routinely used to cover injured tissues in burned patients. Transplantation of hearts and kidneys are no longer considered experimental procedures, and transplantation of bone and connective tissues is routinely done to correct orthopedic deformities.

Bone marrow transplantation is a common treatment for aplastic anemia and is often beneficial in patients with leukemia or lymphoma and patients with certain immune deficiency syndromes.¹ It has been stated that 4000 bone marrow transplantations were performed during 1990² and 7000 during 1991.³

Successful liver transplantation has been beneficial in patients with a variety of parenchymal and congenital diseases of the liver^4,5 and has been used to correct . . . [Full Text PDF of this Article]

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