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A Spin-off From the Helix

C. Thomas Caskey, MD

JAMA. 1993;269(15):1986-1992.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

IN THE 40 years that have passed since the publication of the structure of DNA by Watson and Crick,¹ remarkable new DNA technology has emerged that has prompted the Human Genome Initiative at the National Institutes of Health (NIH) and ushered in the era of molecular medicine. Crick made additional contributions to our understanding of the genetic code, which was elucidated in the 1960s,² and now devotes attention to the study of developmental biology of the central nervous system at the Salk Institute. Watson continues to make contributions to the field of genetics such as training scientists at Harvard and Cold Spring Harbor Laboratories (developing CSHL to modern preeminence) and serving as a visionary leader of the NIH Human Genome Initiative. The scientific community is fortunate to have the continued leadership of Watson and Crick.

In this article, it is my objective to review technological developments in biochemical . . . [Full Text PDF of this Article]

Author Affiliations
From the Institute for Molecular Genetics and Howard Hughes Medical Institute, Baylor College of Medicine, Houston, Tex.

Footnotes
Reprint requests to the Institute for Molecular Genetics and Howard Hughes Medical Institute, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030 (Dr Caskey).

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