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Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults; Scott M. Grundy, MD, PhD; David Bilheimer, MD; Alan Chait, MD; Luther T. Clark, MD; Margo Denke, MD; Richard J. Havel, MD; William R. Hazzard, MD; Stephen B. Hulley, MD, MPH; Donald B. Hunninghake, MD; Robert A. Kreisberg, MD; Penny KrisEtherton, PhD, RD; James M. McKenney, PharmD; Michael A. Newman, MD; Ernst J. Schaefer, MD; Burton E. Sobel, MD; Carolyn Somelofski, MS, RN; Milton C. Weinstein, PhD; H. Bryan Brewer, Jr, MD; James I. Cleeman, MD; Karen A. Donato, MS, RD; Nancy Ernst, MS, RD; Jeffrey M. Hoeg, MD; Basil M. Rifkind, MD; Jacques Rossouw, MD; Christopher T. Sempos, PhD; Joanne M. Gallivan, MS, RD, LD; Maureen N. Harris, MS, RD; Laurie Quint-Adler, MPH, RD

JAMA. 1993;269(23):3015-3023.

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THE SECOND report of the Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel II, or ATP II) presents the National Cholesterol Education Program's updated recommendations for cholesterol management. It is similar to the first in general outline, and the fundamental approach to treatment of high blood cholesterol is comparable. This report continues to identify low-density lipoproteins (LDL) as the primary target of cholesterol-lowering therapy. As in the first report, the second report emphasizes the role of the clinical approach in primary prevention of coronary heart disease (CHD). Dietary therapy remains the first line of treatment of high blood cholesterol, and drug therapy is reserved for patients who are considered to be at high risk for CHD. However, the second report contains new features that distinguish it from the first. These include the following:

1. Increased emphasis on
   

Author Affiliations
From the Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults, National Cholesterol Education Program, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, Md.

Footnotes
Reprint requests to National Cholesterol Education Program, National Heart, Lung, and Blood Institute, National Institutes of Health, Bldg 31, Room 4A-05, Bethesda, MD 20892 (James I. Cleeman, MD).

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