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Kamyar Safdari; Leigh J. Passman, MD, PhD
UCLA School of Medicine Los Angeles, Calif

JAMA. 1993;270(24):2924-2925.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

To the Editor.

—Neaton et al¹ reported that the use of combined pharmacologic and nonpharmacologic intervention is more efficacious and equally safe in the treatment of mild hypertension than nonpharmacologic interventions alone.

In a report of the study design,² TOMHS investigators included cigarette smoking among "etiologically significant major risk factors" for coronary heart disease and cited Multiple Risk Factor Intervention Trial data, which illustrated the increased rate of coronary heart disease mortality among smokers.

An article characterizing TOMHS participants³ reported that 10.9% were cigarette smokers. A subsequent article⁴ reporting results through the first 12 months of the study indicated that cigarette smokers were proportionately randomized to treatment and placebo groups.

The TOMHS investigators did not comment on whether sustained nutritional-hygienic advice to reduce weight, dietary sodium intake, and alcohol intake, and to increase physical activity was accompanied by advice to smokers that they should stop smoking. . . . [Full Text PDF of this Article]

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