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Vasectomy and Increased Risk of Prostate Cancer-Reply
Edward Giovannucci, MD;
Alberto Ascherio, MD;
Eric B. Rimm, ScD;
Graham A. Colditz, MD;
Meir J. Stampfer, MD;
Walter C. Willett, MD
Harvard School of Public Health Boston, Mass
JAMA. 1993;270(6):708.
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In Reply.
—We compared our results of the health professionals with SEER rates as suggested by Sidney et al and found ratios to SEER rates similar to those observed in Kaiser (aged 60 to 64 years, health professionals/SEER rate, 0.84 vs Kaiser/SEER rate, 0.89; aged 65 to 69 years, 0.79 vs 0.91, respectively; aged 70 to 74 years, 0.77 vs 0.77, respectively; and aged 75 to 79 years, 1.00 vs 1.18, respectively). The comparison suggested by Morgentaler and DeWolf does not account for age differences. Further, the prostate-specific antigen test was not widely used for screening when we conducted the studies and, thus, unlikely to have caused bias. The men with and without vasectomy had similar screening histories,1 including frequency of rectal examination, which was the primary screening technique for prostate cancer during the study's time period.
Dr Levine suggests that because of a first encounter with a urologist,
. . . [Full Text PDF of this Article]
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