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II. How to Use an Article About Therapy or Prevention B. What Were the Results and Will They Help Me in Caring for My Patients?

Gordon H. Guyatt, MD, MSc; David L. Sackett, MD, MSc; Deborah J. Cook, MD, MSc; the Evidence-Based Medicine Working Group; Gordon Guyatt, MD, MSc; Eric Bass, MD, MPH; Patrick Brill-Edwards, MD; George Browman, MD, MSc; Deborah Cook, MD, MSc; Michael Farkouh, MD; Hertzel Gerstein, MD, MSc; Brian Haynes, MD, MSc, PhD; Robert Hayward, MD, MPH; Anne Holbrook, MD, PharmD, MSc; Roman Jaeschke, MD, MSc; Elizabeth Juniper, MCSP, MSc; Andreas Laupacis, MD, MSc; Hui Lee, MD, MSc; Mitchell Levine, MD, MSc; Virginia Moyer, MD, MPH; Jim Nishikawa, MD; Andrew Oxman, MD, MSc, FACPM; Ameen Patel, MD; John Philbrick, MD; W. Scott Richardson, MD; Stephane Sauve, MD, MSc; David Sackett, MD, MSc; Jack Sinclair, MD; K.S. Trout, FRCE; Peter Tugwell, MD, MSc; Sean Tunis, MD, MSc; Stephen Walter, PhD; John Williams, Jr, MD, MHS; Mark Wilson, MD, MPH.

JAMA. 1994;271(1):59-63.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

CLINICAL SCENARIO

You are a general internist who is asked to see a 65-year-old man with controlled hypertension and a 6-month history of atrial fibrillation resistant to cardioversion. Although he has no evidence for valvular or coronary heart disease, the family physician who referred him to you wants your advice on whether the benefits of long-term anticoagulants (to reduce the risk of embolic stroke) outweigh their risks (of hemorrhage from anticoagulant therapy). The patient shares these concerns and doesn't want to receive a treatment that would do more harm than good. You know that there have been randomized trials of warfarin for nonvalvular atrial fibrillation and decide that you'd better review one of them. . . . [Full Text PDF of this Article]

Author Affiliations
From the Departments of Medicine and Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario.

Footnotes
Reprint requests to McMaster University Health Sciences Centre, 1200 Main St W, Room 2C 12, Hamilton, Ontario, Canada L8N 3Z5 (Dr Guyatt).

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