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Thomas A. Peterman, MD, MSc; Sevgi O. Aral, PhD
Centers for Disease Control and Prevention Atlanta, Ga

JAMA. 1994;271(17):1318.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

In Reply.

—We thank Dr Gerber and colleagues for their endorsement of our recommendation for more randomized controlled trials of behavior change intervention for HIV and sexually transmitted disease prevention. We also commend the references they cite as excellent overviews of behavioral interventions to prevent HIV. Higgins et al¹ document the paucity of randomized trials. Kelly,² a pioneer in HIV-related community intervention trials, writes: "After more than 12 years of the HIV epidemic—an epidemic that can only be controlled by interventions to promote risk behavior change— the lack of research evaluating outcomes of interventions to prevent HIV infection is very troubling."

Our call for more randomized trials of behavioral interventions has been misinterpreted by some as a statement that behavioral interventions do not work. We believe that some behavioral interventions, like some drug therapy interventions, are effective in some instances. Randomized controlled trials help determine which interventions are . . . [Full Text PDF of this Article]

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