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Jeffrey S. Dover, MD; Kenneth A. Arndt, MD

JAMA. 1994;271(21):1662-1663.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

Since 1976, when Propionibacterium acnes was demonstrated to be uniformly sensitive to the antibiotics used in the treatment of acne, an increasing number of patients with antibiotic-resistant propionibacteria have been described. In a recent British study,¹ cultures of propionibacteria were taken from 468 patients with acne. All patients had received courses of antibiotics in the past; 155 patients had acne that was unresponsive to treatment for at least 3 months. Nearly half of the 468 patients had propionibacteria strains that were resistant to one or more antibiotics; erythromycin resistance was most common (124 patients). All 61 patients with propionibacteria strains that were resistant to tetracycline also showed resistance to doxycycline, but none showed resistance to minocycline. Twenty-seven patients had two or more propionibacteria strains with different antibiotic resistances. The patients who showed a response to antibiotics in this study did not harbor antibiotic-resistant propionibacteria strains.

To avoid the problem . . . [Full Text PDF of this Article]

Author Affiliations
New England Deaconess Hospital and Harvard Medical School, Boston, Mass; Beth Israel Hospital and Harvard Medical School, Boston, Mass

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