This Article  • References  • Full text PDF  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citing articles on HighWire  • Contact me when this article is cited  Related Content  • Similar articles in JAMA  Social Bookmarking   What's this?

Steven J. Martin, PharmD; Dineshchandria Shah, MD
University of Illinois at Chicago

JAMA. 1994;271(24):1905.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

To the Editor.

—Digoxin is one of the most widely used medications in patients with cardiovascular disease. However, hypersensitivity to digitalis-type drugs is extremely rare.^1,2 Reports of cutaneous-type reactions to digitalis products date back to the 1850s, although reactions to the crude extracts of the foxglove plant or Digitalis lanata leaf may represent hypersensitivities to products other than the digitalis compounds.^1-3 The last true report of digitalis hypersensitivity was published more than 35 years ago.¹ Digoxin, digitoxin, and deslanoside are the only cardiac glycosides available today, with digoxin being the nearly exclusive choice for oral and intravenous digitalization. We report herein the case of an elderly man who developed a whole-body rash on initial challenge and subsequent rechallenge with the contemporary formulation of digoxin.

Report of a Case.

—An 86-year-old man was seen in the emergency department after an apparent syncopal episode. Electrocardiographic tracing revealed atrial fibrillation, . . . [Full Text PDF of this Article]

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?