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V. How to Use an Article About Prognosis

Andreas Laupacis, MD, MSc; George Wells, MSc, PhD; W. Scott Richardson, MD; Peter Tugwell, MD, MSc; the Evidence-Based Medicine Working Group; Gordon H. Guyatt, MD, MSc; George Browman, MD, MSc; Deborah Cook, MD, MSc; Hertzel Gerstein, MD, MSc; Brian Haynes, MD, MSc, PhD; Robert Hayward, MD, MPH; Mitchell Levine, MD, MSc; Jim Nishikawa, MD; David L. Sackett, MD, MSc; Patrick Brill-Edwards, MD; Michael Farkouh, MD; Anne Holbrook, MD, PharmD, MSc; Roman Jaeschke, MD, MSc; Hui Lee, MD, MSc; Stephane Sauve, MD, MSc; Virginia Moyer, MD, MPH; David Naylor, MD, DPhil; Andrew Oxman, MD, MSc, FACPM; John Philbrick, MD; Jack Sinclair, MD; Brian L. Strom, MD, MPH; Sean Tunis, MD, MSc; John Williams, Jr, MD, MHS; Mark Wilson, MD, MPH

JAMA. 1994;272(3):234-237.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

CLINICAL SCENARIO

You are about to see a 76-year-old retired schoolteacher for the second time. You first saw her in the clinic a month ago because of cognitive problems. Your evaluation at that time included a Standardized Mini-Mental State Examination,¹ on which she scored 18 out of a possible 30 points, and a physical examination that was normal including no focal neurological signs. You arranged investigations for the treatable causes of dementia that were negative, and you thus feel she has probable Alzheimer's disease.

The patient has lived with her son since her husband died 6 years ago. Her son thinks that she first developed significant problems with her memory about 3 years ago. However, she has become increasingly agitated and paranoid during the last year. She has refused to allow him to look after her financial affairs, despite the fact that she owns three pieces of property and . . . [Full Text PDF of this Article]

Author Affiliations
From the Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario (Dr Laupacis); the Departments of Medicine and Epidemiology and Community Medicine, University of Ottawa (Ontario) (Drs Laupacis, Wells, and Tugwell); and the Department of Medicine, University of Rochester (NY) School of Medicine and Dentistry (Dr Richardson).

Footnotes
Reprint requests to Room 2C12, McMaster University Health Sciences Centre, 1200 Main St W, Hamilton, Ontario. Canada L8N 3Z5 (Dr Guyatt).

Users' Guides to the Medical Literature Section Editor: Drummond Rennie, MD, Deputy Editor (West), JAMA.

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