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  Vol. 273 No. 5, February 1, 1995 TABLE OF CONTENTS
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Helicobacter pylori and Ulcer in Patients Taking NSAIDs

Charles Berkelhammer, MD
Chicago, Ill

JAMA. 1995;273(5):376.

Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

To the Editor.

—The recently published NIH Consensus Conference on Helicobacter pylori in Peptic Ulcer Disease1 asserts that all peptic ulcers associated with H pylori should be treated with an antimicrobial regimen even if the peptic ulcer was associated with the ingestion of aspirin and nonsteroidal anti-inflammatory drugs (NSAIDs). Specifically, it states, "All patients with gastric or duodenal ulcers who are infected with H pylori should be treated with antimicrobials.... The presence of NSAIDs, including aspirin, as a contributing factor should not alter the antimicrobial regimen, but these drugs should be discontinued whenever possible." It concludes, "Ulcer patients with H pylori infection require treatment with antimicrobial agents."

However, I feel that at this time antimicrobial therapy is best considered elective in those H pylori—positive patients who present with their first peptic ulcer while receiving NSAIDs.

NSAID-induced ulcers are common. Whether H pylori infection affects the risk for NSAID-induced . . . [Full Text PDF of this Article]



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