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Robert E. Olson, MD, PhD
University of South Florida College of Medicine Tampa

JAMA. 1995;274(18):1423.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

To the Editor.

—The report of the Dietary Intervention Study in Children (DISC)¹ is an unimpressive account of the hypocholesterolemic effects of low-fat feeding to hypercholesterolemic children 8 to 10 years of age. Rather, it constitutes better support for the proposition that prepubertal boys and girls aged 8 to 10 years with low-density lipoprotein cholesterol (LDL-C) levels at or above the 80th percentile should be permitted to continue their ad libitum diets containing 34% of energy from fat, since after 3 years, the difference in plasma lipoproteins between the two groups was minuscule.

The change in total cholesterol levels in the DISC special intervention group after 3 years was -0.43 mmol/L (-16.7 mg/dL) vs -0.35 mmol/L (-13.6 mg/dL) in the usual care group, a difference of 0.08 mmol/L (3.23 mg/dL). The changes in LDL-C were -0.40 mmol/L (-15.3 mg/dL) vs -0.31 mmol/L (-11.9 mg/dL), a difference of 0.09 mmol/L . . . [Full Text PDF of this Article]

Footnotes
Edited by Margaret A. Winker, MD, Senior Editor, and Phil B. Fontanarosa, MD, Senior Editor.

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