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William Foulkes, MB, PhD; Gordon Glendon, MSc; Steven Narod, MD
Montreal General Hospital Montreal, Quebec

JAMA. 1995;274(5):383.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

To the Editor.

—The recent National Institutes of Health (NIH) Consensus Conference¹ on ovarian cancer provides physicians with the current consensus regarding the screening, treatment, and follow-up of this disease. Therefore, it is important that this document should be as accurate as possible and reflect the opinions of the experts in the field. We agree that a woman has about a 5% lifetime risk of ovarian cancer if she has a first-degree relative affected with ovarian cancer. For example, in Great Britain, one in 120 women develops ovarian cancer. With one affected first-degree relative, the lifetime risk of ovarian cancer is one in 40 (2.5%), representing a relative risk of 3.² In North America, one in 70 women (1.4%) is affected by ovarian cancer, and the relative risk associated with one affected first-degree relative is about 4, giving a lifetime risk of 5.7%.^3,4 However, we disagree with . . . [Full Text PDF of this Article]

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