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No Easy Answers

Margo A. Denke, MD; Margaret A. Winker, MD

JAMA. 1995;274(7):575-577.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

More than a decade ago, randomized placebo-controlled trials proved that reducing elevated cholesterol levels in middle-aged men reduced their risk of coronary heart disease (CHD).^1,2 Whether a similar relationship exists between elevated cholesterol and increased risk of CHD events (defined as hospitalization or death due to CHD) in elderly individuals has remained unclear.^3,4 Data from a cohort of subjects reported by Krumholz and colleagues⁵ and an accompanying Editorial⁶ published in JAMA last year concluded that by at least the age of 80 years, elevated cholesterol no longer confers an increased risk for CHD events.

See also p 539.

In this issue of THE JOURNAL, Corti and colleagues⁷ report an association between elevated cholesterol levels and CHD mortality in elderly women but not in elderly men. To JAMA readers, the methods and results of the study by Corti et al will appear similar to those of Krumholz et . . . [Full Text PDF of this Article]

Author Affiliations
From the University of Texas Southwestern Medical Center, Dallas (Dr Denke), and JAMA, where Dr Winker is a Senior Editor.

Footnotes
Reprint requests to JAMA, 515 N State St, Chicago, IL 60610 (Dr Winker).

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