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J. Perren Cobb, MD; Robert L. Danner, MD

JAMA. 1996;275(15):1192-1196.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

CASE REPORTS

Case 1

A 23-year-old woman presented with a 2-week history of bruising and fever. She was diagnosed as having acute myelogenous leukemia. Three days after beginning chemotherapy, she became disoriented and hypotensive. Her platelet count was 60x10⁹/L, and her white blood cell count was 1.0x10⁹/L, with an absolute neutrophil count of 0.48x10⁹/L. She was resuscitated with 3 L of saline and she was given dopamine at 5 µg·kg^-1·min^-1 and broad-spectrum antibiotics. Her chest radiograph revealed diffuse interstitial-alveolar infiltrates. She required mechanical ventilation for progressive hypoxemia. Pulmonary and radial arterial catheters were inserted and the following hemodynamic parameters were obtained: blood pressure, 90/35 mm Hg; mean arterial pressure (MAP), 53 mm Hg; heart rate, 124 beats per minute; cardiac index, 7.8 L·min^-1·m^-2; central venous pressure (CVP), 12 mm Hg; pulmonary artery pressure, 42/28 mm Hg; pulmonary capillary . . . [Full Text PDF of this Article]

Author Affiliations
From the Critical Care Medicine Department, Warren G. Magnuson Clinical Center, National Institutes of Health, Bethesda, Md. Dr Cobb is now with the Burn, Trauma, and Surgical Critical Care Section, Department of Surgery, Washington University, St Louis, Mo.

Footnotes
Reprints: Robert L. Danner, MD, Critical Care Medicine Department, Warren G. Magnuson Clinical Center, Bldg 10, Room 7D-43, National Institutes of Health, Bethesda, MD 20892.

Grand Rounds at the Clinical Center of the National Institutes of Health section editors: John I. Gallin, MD, the Clinical Center of the National Institutes of Health, Bethesda, Md; David S. Cooper, MD, Contributing Editor, JAMA.

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