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Jane A. Driver, MS, BA; Jerry Lynn, MD; Upendra S. Dhanjal, MD
University of Pittsburgh Medical Center Pittsburgh, Pa

JAMA. 1996;276(15):1221-1222.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

To the Editor.

—Dapsone and primaquine phosphate are commonly used in the prophylaxis and treatment of Pneumocystis carinii pneumonia (PCP) in patients with human immunodeficiency virus (HIV) infection. A 42-year-old man with AIDS presented with a 2-week history of fever, chills, shortness of breath, and nonproductive cough. The chest x-ray film revealed a diffuse fine infiltrate suggestive of PCP. The diagnosis was later confirmed with bronchoalveolar lavage. On admission, an arterial blood gas analysis revealed a pH of 7.43, Pco₂ of 35.2 mm Hg, Po₂ of 82.5 mm Hg, and arterial blood oxygen saturation (sAO₂) of 89.2% on room air. The CD4⁺ cell count was 0.018X10⁹/L (18/µL). The patient was allergic to sulfa drugs and had been taking oral dapsone (100 mg daily) as PCP prophylaxis for the past 5 years. He was started on intravenous clindamycin (900 mg, 3 times daily) and primaquine . . . [Full Text PDF of this Article]

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