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R. Daniel Braun, MD
Indiana University School of Medicine Indianapolis

JAMA. 1996;276(15):1222.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

To the Editor.

—Dr Morrison and colleagues¹ take little or no note of what I find to be a very important aspect of the data presented in their article. The folate data for men (in Table 3) show a relative risk (RR) of 1.36 (95% confidence interval [CI], 0.80-2.31) for those in the lowest quartile when compared with those in the highest quartile. In contrast, the data for women (presented in Table 4) show an RR of 2.83 (95% CI, 1.30-6.18) for women in the lowest quartile as compared with those in the highest quartile.

Although the authors mention these data, they also comment that, "there was no statistically significant interaction by sex." I am unable to find anything in the article to justify this statement. Moreover, in the "Comment," the authors state, "It is not known if the increased RR in women as compared with men was a . . . [Full Text PDF of this Article]

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