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Grafts vs Fistulas for Hemodialysis PatientsEqual Access for All?
Glenn M. Chertow, MD, MPH
JAMA. 1996;276(16):1343-1344.
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| Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings. |
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Long-term vascular access is required in all hemodialysis patients in order to achieve blood flow rates sufficient for removal of metabolic by-products (eg, urea, creatinine, and other nitrogenous compounds) and excess plasma water. There are 2 principal means of creating permanent vascular access for hemodialysis: an endogenous arteriovenous fistula (also known as a shunt), described initially by Brescia et al,1 using an end-to-side anastomosis of the cephalic vein and radial artery, and a synthetic polytetrafluoroethylene (PTFE) arteriovenous graft, preferably placed in the distal upper extremity. Randomized clinical trial data comparing these 2 types of vascular access have not been performed, but many years of clinical experience and several observational studies have shown a marked increase in the rate of complications and access failure with PTFE grafts, due primarily to repeated bouts of thrombosis and infection.2-5 As of December 1993, only 44% of patients initiating hemodialysis had undergone placement
. . . [Full Text PDF of this Article]
Author Affiliations
From the Renal Division, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Mass.
Footnotes
Reprints: Glenn M. Chertow, MD, MPH, Dialysis Unit Administrative Office, Brigham and Women's Hospital, 75 Francis St, Boston, MA 02115.
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