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Prudencio Martinez, PharmD, PhD; Raul Ortiz de Lejarazu, MD, PhD; Jose Maria Eiros, MD, PhD; Antonio Rodriguez-Torres, MD, PhD
University Hospital of Valladolid Valladolid, Spain

JAMA. 1997;277(20):1592.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

To the Editor.

—We read the article by Ms Gallo and associates¹ about the new oral specimen collection device for HIV testing with great interest. We would like to contribute our experience in diagnosis of HIV infection using fluids other than serum (ie, OMT and urine). We analyzed 185 paired serum, gingivocrevicular transudate, and urine samples from individuals infected with HIV-1 (69 of whom were Centers for Disease Control and Prevention [CDC] stage II, 15 CDC stage III, and 30 CDC stage IV) and 71 noninfected individuals, blood donors from the hematology service of our hospital. We used an oral device consisting of a cylinder of cotton wool without preservative (Salivette, Sarstedt, Leicester, United Kingdom). Sample preservation was ensured by refrigeration.

Individuals participating in the study were informed about the importance of proper pad placement in the gingivocrevicular fold and also that the pad should be removed from the mouth when it . . . [Full Text PDF of this Article]

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