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Jeremiah Stamler, MD
Northwestern University Medical School Chicago, Ill

William B. Applegate, MD, MPH
University of Tennessee Memphis

Jerome D. Cohen, MD
St Louis University St Louis, Mo

Jeffrey A. Cutler, MD
National Heart, Lung and Blood Institute Bethesda, Md

Paul K. Whelton, MD, MSc
Tulane University School of Public Health New Orleans, La

JAMA. 1997;277(20):1594-1595.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

To the Editor.

—Several statements in the letter by Dr Logan and colleagues¹ on dietary sodium and blood pressure (BP) require clarification and correction. First, the authors assert "studies including Intersalt (particularly when data from the 4 primitive societies have been excluded) have found, however, no consistent relationship."¹ In Intersalt analyses on individuals, results were consistent for 10 074 persons from all 52 samples and for 9343 persons from 48 samples (excluding 4 low-sodium samples); the multivariate controlled coefficients for the sodium-systolic BP relationship were—3.1 mm Hg (P<.001) and -3.2 mm Hg (P<.001), respectively for a 24-hour urinary sodium level 100 mmol/d lower (or -6.0 and -6.2 mm Hg without adjustment for body mass index).² Results also were similar for nonhypertensives,² indicating that "salt sensitivity" is prevalent throughout the population and is not confined mainly to hypertensives.

In multivariate cross-population analyses (n=52 and n=48), . . . [Full Text PDF of this Article]

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