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Jorge Salmerón, MD
Instituto Mexicano del Seguro Social Mexico, DF

JAMA. 1997;277(22):1762.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

In Reply.

—As Dr Maki and colleagues point out, experimental and metabolic studies offer strong evidence supporting a beneficial short-term effect of high-fiber diets on glucose metabolism. In patients with NIDDM, this effect appears to be greater for purified viscous soluble fiber than for less viscous fibers.¹ However, among healthy subjects, short-term supplementation of nonviscous fibers seems to have a greater beneficial effect on glucose tolerance than do viscous fibers.²

In our study population, the main source of dietary fiber is cereals, and more than 75% of this fiber is insoluble. However, the main sources of insoluble fibers are also the important sources of soluble fiber; thus the intakes of these components are highly correlated (r=0.89). When we compared the lowest and highest quintiles of energy-adjusted intakes, insoluble fiber was inversely associated with risk of diabetes (RR, 0.76; 95% CI, 0.61-0.95) after controlling for other important factors—whereas soluble fiber . . . [Full Text PDF of this Article]

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