This Article  • References  • Full text PDF  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Contact me when this article is cited  Related Content  • Similar articles in JAMA  Social Bookmarking   What's this?

Aryeh Hurwitz, MD; Constance Ruhl, MD, MPH
University of Kansas Medical Center Kansas City

JAMA. 1997;278(20):1659-1660.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

The studies by Dr Russell and colleagues have added to our appreciation that achlorhydria, resulting from either omeprazole administration or atrophic gastritis, can cause malabsorption of protein-bound vitamin B₁₂.¹ Though we did not determine absorption or levels of vitamin B₁₂, we do not share his view that our data show one third of elderly Americans to be at risk of malabsorption of food-bound vitamin B₁₂. Six (2%) of our 248 subjects were receiving vitamin B₁₂ injections, 4 of whom had low basal acidity by the resin test (urine quinine <90 pg in 2 hours) and severe atrophic gastritis (serum pepsinogen [PG] I <20 pg/L). In the other 2 subjects, both parameters were normal. Twenty-two (9%) of 243 elderly subjects had PG I/PG II ratios less than 2.9, indicating atrophic gastritis. None was anemic. Those who had severe atrophic gastritis (PG I 20 pg/L) (n=11) also . . . [Full Text PDF of this Article]

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?