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Meera Mahalingam, MD, PhD
Mallory Institute of Pathology Boston Medical Center

Michael E. Ottlinger, PhD
VA Medical Center Boston, Mass

JAMA. 1997;278(24):2143-2144.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

To the Editor.

—Cardiac troponin T (cTnT) thought to be a more specific indicator of myocardial cell necrosis than serum creatine kinase—MB (CK-MB).^1-3 The CardiacT assay is the Food and Drug Administration—approved point-of-care device increasingly used in the detection of cTnT. To our knowledge, this is the first report of a case in which the CardiacT assay failed to detect myocardial infarction (MI) in contradiction to other biochemical markers.

A 79-year-old man, with a history of non-Q wave MI and chronic stable angina diagnosed 7 years earlier, presented to the emergency department with complaints of chest pain while walking. Cardiac examination showed a normal S₁, S₂, no S₃, and a grade 2/4 harsh systolic murmur that was heard best at the right upper sternal border. A 12-lead electrocardiogram (ECG) demonstrated a sinus rhythm with a rate of 92 and right bundle branch block. Laboratory data are . . . [Full Text PDF of this Article]

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RELATED LETTER

False-Negative Qualitative Troponin T
Joël Belmin, Smahane Medjahed, Anne Bruhat, Michael E. Ottlinger, and Meera Mahalingam
JAMA. 1998;279(16):1262-1263.
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