This Article  • References  • Full text PDF  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Contact me when this article is cited  Related Content  • Similar articles in JAMA  Social Bookmarking   What's this?

H. Ballentine Carter, MD
Johns Hopkins Hospital Baltimore, Md

JAMA. 1997;278(9):701.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

To the Editor.

—Dr Moul has compared a series of black men (at Walter Reed Hospital) who underwent radical prostatectomy for both palpable and nonpalpable prostate cancers with our series of men (at Johns Hopkins Hospital) with only nonpalpable prostate cancers who underwent radical prostatectomy. It is well known that men with nonpalpable prostate cancer have a greater chance of cure with surgery and thus the 2 series are not comparable. The PSA level that will both maintain the detection of curable prostate cancer and minimize the detection of insignificant cancers is unknown. Our data—based primarily on white men—suggest that this level is 4.0 ng/mL in the setting of a nonsuspicious digital rectal examination, and that below this level the risk of detecting small cancers is high. The recently published data demonstrating a 22% cancer detection rate in men (mostly white) with a PSA level between 2.6 and 4.0 ng/mL also demonstrate . . . [Full Text PDF of this Article]

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?