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RELIEF BY IRRIGATION AND CONTROL OF ALKALOSIS: PRELIMINARY REPORT

MILTON M. PORTIS, M.D.; BERNARD PORTIS, M.D.

J Am Med Assoc. 1925;85(8):574-576.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

Acute duodenal obstruction is now assuming great importance because of the performance of more radical gastric surgery and of the newer conceptions of alkalosis and gastric tetany. We have attempted in this experimental study to produce an artificial duodenal obstruction and to remove the toxic substance by irrigation and to determine the relative importance of the involved factors.

The literature contains numerous reports regarding high intestinal obstruction and the effects caused by closed loops of intestine at different levels. Neuman¹ first described the usual syndrome in 1861, and Kussmaul² later confirmed his observations. Many have observed a profound and even rapidly fatal intoxication caused by substances formed in an obstructed bowel. The higher the obstruction, the more rapid and toxic the picture. Obstructions in the duodenum are rapidly fatal.

All are agreed that the severe reaction following high intestinal obstruction is due to some highly toxic substance. The . . . [Full Text PDF of this Article]

Author Affiliations
CHICAGO

From the Hull Physiologic Laboratory, University of Chicago.

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