THERAPEUTIC AGENTS IN LIVER DISEASE
A Review of Medicinal Agents
- DWIGHT L. WILBUR, M.D.
Since this article does not have an abstract, we have provided the first 150 words of the full text.
Excerpt
The functions of the normal and diseased liver are surprisingly little affected by the action of drugs which are not hepatotoxic. In fact, in regard to the activity of drugs the striking action is that of the liver on them and not of the drugs on the liver, and one might well entitle this paper "The Effect of the Liver on Drugs" rather than "The Effect of Drugs on the Liver." Clark1 has well summarized the situation by stating that "few means are known by which the functions of the liver can be stimulated or aided by means of drugs."
In the index of "A Manual of Pharmacology" Sollmann2 has listed under the title, "Liver," only three subjects, namely "antianemic preparations," "extractsaline" and "liver of sulfur." A brief review of the subject indicates clearly that, with the exception of certain specific drugs used in the treatment of diseases
Footnotes
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Read in a symposium on "Diseases of the Liver" before the joint meeting of the Section on Gastro-Enterology and Proctology and the Section on Pathology and Physiology at the Ninety-Fifth Annual Session of the American Medical Association, San Francisco, July 5, 1946.
