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JAMA. 1953;153(15):1351-1356. doi: 10.1001/jama.1953.02940320023007

PHYSIOLOGICAL AND CLINICAL ASPECTS OF CONCEPTION

  1. Edward T. Tyler, M.D.
  1. Los Angeles
  2. From the School of Medicine, the University of California at Los Angeles.; Chief, Endocrine Clinic, Los Angeles County Harbor General Hospital, Torrance, Calif.

Since this article does not have an abstract, we have provided the first 150 words of the full text.

Excerpt

Medical research in the past few decades has made great strides, and as a result many physiological and pathological processes have been clarified to a remarkable degree. Yet, some of the most basic biological phenomena have stubbornly resisted laboratory and clinical investgation, with real progress occurring only in slow and painstaking stages. In this class is the phenomenon of human reproduction. Although there have been numerous and varied recent attempts to elaborate on the mechanism of this complicated process, there is much that is still obscure. This report reviews certain of the known aspects of normal reproduction and attempts to correlate these with a number of conditions found in clinical infertility.

In the male, endocrine stimulation from the anterior pituitary is responsible for normal testicular function, including the production of male sex hormone or hormones and sperm. The pituitary follicle-stimulating fraction (F. S. H.), under hypothalamic influence, is believed to

Footnotes

  • Portions of these studies were aided by a grant from the Ortho Research Foundation.

  • Read before the Section on Obstetrics and Gynecology at the 102nd Annual Meeting of the American Medical Association, New York, June 3, 1953.

  • The estradiol trimethylacetate (Estrotate), progesterone, and chorionic gonadotropin (Choriogonin) were supplied by Dr. H. L. Daiell, Lakeside Laboratories, and the ethisterone (Pranone) by Dr. Edward Henderson, Schering Corporation.

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