γ-Globulin in the Prophylaxis of Posttransfusion Hepatitis
- Paul V. Holland, MD;
- Richard M. Rubinson, MD;
- Andrew G. Morrow, MD;
- Paul J. Schmidt, MD
Abstract
Commercial γ-globulin given shortly before open-heart surgery and then one month later was ineffective in reducing the incidence of posttransfusion icteric hepatitis. There were 11 cases in 84 treated patients, 6 in 83 control patients. Half of the cases of hepatitis had an incubation period of less than 50 days and neither this nor the severity of disease was affected by the γ-globulin treatment.
Footnotes
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Read in part before the annual meeting of the American Association of Blood Banks, Miami, Fla, September 1965.
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Reprint requests to Blood Bank Department, Clinical Center, National Institutes of Health, Bethesda, Md 20014 (Dr. Holland).
