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JAMA. 1969;209(2):243-248. doi: 10.1001/jama.1969.03160150029007

Chronic Plumbism in Children

Diagnosis by Hair Analysis

  1. Louis Kopito, MS;
  2. Ann M. Briley, MD;
  3. Harry Shwachman, MD
  1. From the Division of Clinical Laboratories and the Department of Medicine, Children's Hospital Medical Center, the Department of Pediatrics, Harvard Medical School, and the Children's Cancer Research Foundation, Boston; and the Martha M. Eliot Health Center, Jamaica Plain, Mass.

Abstract

The determination of lead in scalp hair is a valuable diagnostic aid in chronic or mild lead intoxication particulary when the other clinical or laboratory evidence is of questionable diagnostic quality. This continuously growing tissue accumulates and stores lead for long periods and may be used for estimating the time and duration of the exposure. Hair is easy to obtain, store, transport, and analyze and may provide a practical means for finding little children who may have been exposed to lead.

Footnotes

  • Reprint requests to 300 Longwood Ave, Boston 02115 (Dr. Shwachman).

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