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JAMA. 1972;221(1):36-41. doi: 10.1001/jama.1972.03200140024007

Audibility of the Fourth Heart Sound

A Prospective, "Blind" Auscultatory and Polygraphic Investigation

  1. Eulogio H. Rectra, MD;
  2. Abdul H. Khan, MD;
  3. Veronica M. Pigott, MS;
  4. David H. Spodick, MD
  1. From the Cardiology Division, Medical Service, Lemuel Shattuck Hospital, and the Department of Medicine, Tufts University School of Medicine, Boston.

Abstract

An auscultatory search for a fourth heart sound (S4) was performed by two independent "blind" auscultators who did not know the medical status of 196 consecutively examined subjects, ages 50 to 80 years. Phonocardiograms (PCGs) and other tracings taken after recording the results were measured by a third observer who was also "blind." Results of this investigation indicate that any tendency for rapid completion of atrial excitation and early onset of S4 appears to determine the auscultatory audibility of the fourth heart sound. Conversely, a tendency to later completion of atrial excitation and a later onset of S4 will make it auscultatorily inaudible, although recordable even at considerable amplitude by PCG. The relative amplitude and frequency of S4 were not significantly related to its audibility. The presence or absence of disease was not significantly related to the presence or absence of S4 by PCG or to its audibility when present.

Footnotes

  • Reprint requests to 170 Morton St, Boston 02130 (Dr. Spodick).

  • Read in part before the American Heart Association 44th scientific sessions, Anaheim, Calif, Nov 10, 1971.

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