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Brief Report
JAMA. 1975;234(9):948-949. doi: 10.1001/jama.1975.03260220052019

Migration of Plasticizer From Hemodialysis Blood Tubing

Preliminary Report

  1. Keiji Ono, MD;
  2. Ryo Tatsukawa, PhD;
  3. Tadaaki Wakimoto, PhD
  1. From the Department of Surgery and the Kidney Center, Fukuoka Municipal Daiichi Hospital, Fukuoka (Dr Ono), and Department of Agricultural Chemistry, Faculty of Agriculture, Ehime University, Matsuyama, Ehime (Drs Tatsukawa and Wakimoto), Japan.

Abstract

Di-2-ethylhexyl phthalate was found to be migrating from polyvinyl chloride blood tubing into human blood during hemodialysis in 16 patients with end-stage renal failure. Although toxic effects have not yet been observed, we believe plastic tubing that does not contain extractable materials should be developed.

(JAMA 234:948-949, 1975)

Footnotes

  • Reprint requests to 1-8-1 Yoshizuka Hakata-Ku Fukuoka, Japan 812 (Dr Ono).

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