Drug Therapy of Hyperlipoproteinemia
- Robert I. Levy, MD
Since this article does not have an abstract, we have provided the first 150 words of the full text.
Excerpt
MANAGEMENT of hyperlipoproteinemia has been advanced considerably in recent years through new insights into lipid and lipoprotein metabolism, as well as into the mode of action of hypolipidemic drugs.1 A variety of highly effective lipid levellowering drugs is now available.2 Because of the heterogeneity of the hyperlipoproteinemias, no single drug is useful in all the disorders. We now know that elevated lipid levels are the result of increased production or decreased removal of specific lipoproteins. Thus, the efficacy of a specific drug is determined by its effect on production or removal of the lipoproteins present in excess in each type of hyperlipoproteinemia.3
Hypolipidemic drugs can control hyperlipoproteinemia by one of two
Footnotes
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Reprint requests to National Heart and Lung Institute, Bethesda, MD 20014 (Dr Levy).
