Multiple Myeloma and Multiple Neoplasms
Since this article does not have an abstract, we have provided the first 150 words of the full text.
Excerpt
SIMULTANEOUS multiple primary neoplasms in a single individual are increasingly being recognized. Disordered immune surveillance might render patients to be unusually susceptible to the development of multiple tumors.1 We report a patient with multiple myeloma who had at least three other primary neoplasms.
Report of a Case An 83-year-old man had weight loss, bone pain, and anemia (hematocrit value, 22.7%). Protein electrophoresis showed a monoclonal spike in the gamma region. Immunoelectrophoresis demonstrated increased IgG levels (6.6 gm/100 ml) and decreased IgA and IgM levels. Urine immunoelectrophoresis showed an increased IgG level and lambda light chains. Bone marrow biopsy specimens showed a hypercellular marrow, with sheets of plasma cells comprising 50% of the cellular population. The serum calcium concentration was 12 mg/100 ml and serum phosphate and alkaline phosphatase levels were within normal limits. Stools were 4 + guaiac positive. The patient was treated with hydration, sodium biphosphate and a regimen
Footnotes
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Reprint requests to the Boston Veterans Administration Hospital, 150 S Huntington Ave, Jamaica Plain, MA 02130 (Dr Chopra).
