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Original Contribution
JAMA. 1976;236(3):263-265. doi: 10.1001/jama.1976.03270030017019

Bacteremic Infections Due to Clindamycin-Resistant Streptococci

  1. Mark S. Drapkin, MD;
  2. Adolf W. Karchmer, MD;
  3. Robert C. Moellering Jr, MD
  1. From the Department of Medicine, Harvard Medical School, and the Department of Medicine, Massachusetts General Hospital, Boston. Dr Drapkin is now at the Department of Medicine, Tufts University School of Medicine, Boston, and the Newton-Wellesley Hospital, Newton Lower Falls, Mass.

Abstract

We have recently observed four patients with bacteremic infections due to group A streptococci that were highly resistant to clindamycin and only moderately susceptible to erythromycin. Two of the infections developed while the patients were receiving clindamycin. The organisms were not β-hemolytic under standard conditions nor were they M or T typable. We urge that all streptococci isolated from patients with serious infections be grouped serologically and be tested for antibiotic susceptibilities, especially if therapy with antibiotics other than penicillin is to be considered.

(JAMA 236:263-265, 1976)

Footnotes

  • Reprint requests to Massachusetts General Hospital, Boston, MA 02114 (Dr Karchmer).

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