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Trends in Therapy
JAMA. 1977;238(12):1289-1290. doi: 10.1001/jama.1977.03280130071025

Evaluation of Cimetidine (Tagamet)

An Antagonist of Hydrochloric Acid Secretion

  1. Charles B. Clayman, MD
  1. Dr Clayman is Senior Scientist, AMA Department of Drugs. This communication was prepared with the assistance of consultants.

Abstract

Cimetidine, a potent H2-receptor antagonist, has been introduced for the treatment of various conditions associated with acid peptic digestion in the gastrointestinal tract. Preliminary results are encouraging. Adverse reactions do not appear to be substantial; however, the effect of long-term use has yet to be ascertained.

(JAMA 238:1289-1290, 1977)

Footnotes

  • Scientific data on cimetidine were supplied by Smith Kline & French Laboratories, Philadelphia.

  • Reprint requests to Department of Drugs, American Medical Association, 535 N Dearborn St, Chicago, IL 60610.

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