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Original Contribution
JAMA. 1979;241(26):2793-2797. doi: 10.1001/jama.1979.03290520017017

Chest Wall Syndrome

A Common Cause of Unexplained Cardiac Pain

  1. Stephen E. Epstein, MD;
  2. Lynn H. Gerber, MD;
  3. Jeffrey S. Borer, MD
  1. From the Cardiology Branch (Drs Epstein and Borer), National Heart, Lung, and Blood Institute, and the Rehabilitation Department (Dr Gerber), Clinical Center, National Institutes of Health, Bethesda, Md.

Abstract

Twelve patients with severe, often incapacitating chest pain initially believed to be cardiac in origin were shown on subsequent evaluation to have chest wall syndrome. Diagnosis was suspected by the atypical nature of pain in 11 of 12 patients and confirmed by chest wall tenderness simulating the spontaneously occurring pain in all. Seven patients had chest wall syndrome in conjunction with other associated cardiac conditions. Five patients had isolated chest wall syndrome. All five had normal ejection fractions and no regional wall abnormalities on radionuclide cineangiographic studies performed during symptom-limited supine exercise, findings observed in few patients with coronary artery disease. Chest wall syndrome should be considered in all patients with chest pain, as its recognition can greatly aid in patient care.

(JAMA 241:2793-2797, 1979)

Footnotes

  • Reprint requests to Cardiology Branch, National Institutes of Health, Bldg 10, Room 7B-15, Bethesda, MD 20014 (Dr Epstein).

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