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Original Contribution
JAMA. 1979;242(17):1882-1884. doi: 10.1001/jama.1979.03300170028021

Cytotoxic-lnduced Ovarian Failure in Hodgkin's Disease

II. Effects on Sexual Function

  1. Ramona M. Chapman, MD;
  2. Simon B. Sutcliffe, MD, MRCP;
  3. James S. Malpas, DPhil, FRCP
  1. From the Imperial Cancer Research Fund, Department of Medical Oncology, St Bartholomew's Hospital, West Smithfield, London.

Abstract

Chemotherapy for Hodgkin's disease produces ovarian failure in young women. The consequences of this are emotional distress, sexual dysfunction, and the disruption of families and friendships. These previously unappreciated side effects of cytotoxic therapy had developed in 25 of 41 patients, among whom we conducted a retrospective study.

(JAMA 242:1882-1884, 1979)

Footnotes

  • This material was presented in part before a meeting of the Royal Society of Medicine, London, Dec 20, 1978.

  • Reprint requests to Hematology-Oncology Service, Walter Reed Army Medical Center, Washington, DC 20012 (Dr Chapman).

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