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Brief Report
JAMA. 1980;243(20):2058-2060. doi: 10.1001/jama.1980.03300460040024

Mitochondrial Creatine Kinase

A Poor Prognostic Sign

  1. C. Jack Bark, MD
  1. From the Alvarado Community Hospital and the Department of Pathology, University of California, San Diego.

Abstract

A serum creatine kinase (CK) isoenzyme band cathodic to MM, thought to represent mitochondrial CK, was found in eight patients in shock, six of whom died within 12 days. Severe tissue damage appears to be required to release this isoenzyme to detectable levels in the serum.

(JAMA 243:2058-2060, 1980)

Footnotes

  • Reprint requests to Alvarado Community Hospital, 6655 Alvarado Rd, San Diego, CA 92120 (Dr Bark).

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