Alcohol Consumption in a Healthy Population
Relationship to γ-Glutamyl Transferase Activity and Mean Corpuscular Volume
- Laure Papoz, MS;
- Jean-M. Warnet, PhD;
- Georges Péquignot, MD;
- Eveline Eschwege, MD;
- Jean R. Claude, PhD;
- Daniel Schwartz, PhD
- From Unité de Recherches Statistiques (Drs Papoz, Eschwege, and Schwartz) and Section Nutrition, Division de la Recherche Médico-Sociale (Dr Péquignot), Institut National de la Santé et de la Recherche Médicale (INSERM), Villejuif, and Laboratoire de la Direction des Affaires Sanitaires et Sociales (DASS) (Drs Warnet and Claude), Paris.
Abstract
We analyzed the multivariate relationship between alcohol consumption and γ-glutamyl-transferase (GGT), mean corpuscular volume (MCV), and tobacco consumption. A group of 995 healthy outpatients (604 men and 391 women, 18 to 76 years old) were systematically examined. Daily alcohol consumption was established after an interview regarding complete dietary habits. Significant correlations have been found between daily alcohol intake and corresponding GGT and MCV values, 35 and 34, respectively, in men and 24 and 21 in women. Multiple regression analyses confirm the superiority of GGT over MCV as a laboratory marker of alcohol intake and show the advantage of using them together. A rough estimation of alcohol consumption is proposed as a first step in mass screening of heavy drinkers.
(JAMA 1981;245:1748-1751)
Footnotes
-
Reprint requests to Unité de Recherches Statistiques, INSERM, 16 bis av. Paul Vaillant Couturier, 94800 Villejuif, France (Dr Schwartz).
